BMS 182874 [153042-42-3]

MedChem Express

BMS 182874 [153042-42-3]

14

153042-42-3

Research Use Only

99.85

C17H19N3O3S

345.42

BMS 182874 is an orallyactive, highly selective endothelin receptor (ETA receptor) antagonist, with IC50 value of 0.150 microM, Ki of 0.055 microM. BMS 182874 reduces the arterial pressure of Deoxycorticosterone acetate (HY-B1472) induced hypertension model in rats, and can be used for cardiovascular disease research[1].

O=S(C1=C2C=CC=C(C2=CC=C1)N(C)C)(NC3=C(C(C)=NO3)C)=O

2°C to 8°C

12352200