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BMS 182874 [153042-42-3]

BMS 182874 [153042-42-3]

T26841
TargetMol Chemicals
CAS Number153042-42-3
Product group Chemicals
Estimated Purity98.38%
Molecular Weight345.42
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    BMS 182874 [153042-42-3]
  • Delivery Days Customer
    4
  • CAS Number
    153042-42-3
  • Certification
    Research Use Only
  • Chemical Name
    BMS 182874
  • Estimated Purity
    98.38%
  • Molecular Formula
    C17H19N3O3S
  • Molecular Weight
    345.42
  • Scientific Description
    BMS 182874 is an orally effective and highly selective endothelin receptor ETA antagonist with an IC50 value of 0.150 microM for ETA and a Ki value of 0.055 microM for ETA.BMS 182874 is able to reduce arterial pressure in a rat hypertension model induced by Deoxycorticosterone acetate. BMS 182874 was able to reduce Deoxycorticosterone-induced arterial pressure in a rat model of hypertension and can be used to study cardiovascular disease.
  • Shelf life instruction
    3 years
  • SMILES
    S(NC1=C(C)C(C)=NO1)(=O)(=O)C=2C3=C(C(N(C)C)=CC=C3)C=CC2
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200