Bortezomib

Selleck Chemicals

Bortezomib (PS-341) [179324-69-7]

9

179324-69-7

Research Use Only

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Bortezomib is a potent 20S proteasome inhibitor with Ki of 0.6 nM. It exhibits favorable selectivity towards tumor cells over normal cells. Bortezomib (PS-341) inhibits NF-kappaB and induces ERK phosphorylation to suppress cathepsin B and inhibit the catalytic process of autophagy in ovarian cancer and other solid tumors.

-20°C,-80°C

51202000