Bio-Connect

BQ-123 [136553-81-6]

HY-12378
MedChem Express
CAS Number136553-81-6
Product group Chemicals
Estimated Purity95.3%
Molecular Weight610.7
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BQ-123 [136553-81-6]
  • Delivery Days Customer
    10
  • CAS Number
    136553-81-6
  • Estimated Purity
    95.3%
  • Molecular Formula
    C31H42N6O7
  • Molecular Weight
    610.7
  • Scientific Description
    BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM and a Ki of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension.
  • SMILES
    O=C(N[C@](C(N(CCC1)[C@]1([H])C2=O)=O)([H])CC(O)=O)[C@H](NC([C@@H](NC([C@H](N2)C(C)C)=O)CC(C)C)=O)CC3=CNC4=CC=CC=C34
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200