BQ-123 [136553-81-6]

HY-12378
Overview
- SupplierMedChem Express
- Product NameBQ-123 [136553-81-6]
- Delivery Days Customer10
- CAS Number136553-81-6
- CertificationResearch Use Only
- Estimated Purity99.78
- Molecular FormulaC31H42N6O7
- Molecular Weight610.70
- Scientific DescriptionBQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM and a Ki of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension[1][2][3].
- SMILESO=C(N[C@](C(N(CCC1)[C@]1([H])C2=O)=O)([H])CC(O)=O)[C@H](NC([C@@H](NC([C@H](N2)C(C)C)=O)CC(C)C)=O)CC3=CNC4=CC=CC=C34
- Storage Instruction-20°C,-80°C
- UNSPSC12352200