BRD4770
HY-16705
CAS Number1374601-40-7
Product group Chemicals
Estimated Purity99.69
Molecular Weight413.47
Overview
- SupplierMedChem Express
- Product NameBRD4770 [1374601-40-7]
- Delivery Days Customer10
- CAS Number1374601-40-7
- Estimated Purity99.69
- Molecular FormulaC25H23N3O3
- Molecular Weight413.47
- Scientific DescriptionBRD4770 is a histone methyltransferase G9a inhibitor. BRD4770 reduces di- and trimethylation of lysine 9 on histone H3 (H3K9) with an EC 50 of 5 microM, and has less or little effect toward H3K27me3, H3K36me3, H3K4me3, and H3K79me3. BRD4770 can activate the ataxia telangiectasia mutated (ATM) pathway and induce cell senescence [1] .
- SMILESO=C(C1=CC=C2C(N=C(NC(C3=CC=CC=C3)=O)N2CCCC4=CC=CC=C4)=C1)OC
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200