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Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA865097LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA865097LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA865097LA01HU at dilution of 1:100

BRD7 Antibody

Research Use Only
CSB-PA865097LA01HU
Cusabio
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetBRD7
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Overview

  • Supplier
    Cusabio
  • Product Name
    BRD7 Antibody
  • Delivery Days Customer
    20
  • Applications
    ImmunoFluorescence, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID29117
  • Target name
    BRD7
  • Target description
    bromodomain containing 7
  • Target synonyms
    75 kDa bromodomain protein; BP75; bromodomain-containing protein 7; CELTIX1; NAG4; protein CELTIX-1; SMARCI1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NPI1
  • Protein Name
    Bromodomain-containing protein 7
  • Scientific Description
    Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at \\\Tyr-216\\\. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at \\\Lys-9\\\ (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at \\\Lys-382\\\, and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203