BRG1 antibody
GTX132121
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetSMARCA4
Overview
- SupplierGeneTex
- Product NameBRG1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.82 mg/ml
- ConjugateUnconjugated
- Gene ID6597
- Target nameSMARCA4
- Target descriptionSWI/SNF related BAF chromatin remodeling complex subunit ATPase 4
- Target synonymsBAF190, BAF190A, BRG1, CSS4, MRD16, OTSC12, RTPS2, SNF2, SNF2-beta, SNF2L4, SNF2LB, SWI2, hSNF2b, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4, ATP-dependent helicase SMARCA4, BRG1-associated factor 190A, BRM/SWI2-related gene 1, SNF2-like 4, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4, brahma protein-like 1, global transcription activator homologous sequence, homeotic gene regulator, mitotic growth and transcription activator, nuclear protein GRB1, protein BRG-1, protein brahma homolog 1, sucrose nonfermenting-like 4, transcription activator BRG1
- HostRabbit
- IsotypeIgG
- Protein IDP51532
- Protein NameTranscription activator BRG1
- Scientific DescriptionThe protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203


![IP analysis was perform with HeLa lysates and either control IgG or BRG1 antibody [4E11-E11-G11]. The precipitates were detected by the same antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX16472/GTX16472_IP_w_23060620_484.webp)


![ICC/IF analysis of 4% PFA-fixed HeLa cells using GTX66842 BRG1 antibody [6D7]. Blue : DAPI Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX66842/GTX66842_20190305_ICCIF_w_23061221_592.webp)
![WB analysis of various samples using GTX80217 BRG1 antibody [BRG-01]. Panel A : Brg1-negative SW13 cells transfected with Brg1 Panel B : HEK293 cytoplasmic (cyt) and nuclear (nuc) lysates](https://www.genetex.com/upload/website/prouct_img/normal/GTX80217/GTX80217_20191028_WB_1_w_23061322_611.webp)
