C-021

MedChem Express

C-021 [864289-85-0]

10

864289-85-0

Research Use Only

99.95

C27H41N5O2

467.65

C-021 is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 potently inhibits functional chemotaxis in human and mouse with IC 50 s of 140 nM and 39 nM, respectively. C-021 effectively prevents human CCL22-derived [ 35 S]GTPgammaS from binding to the receptor with an IC 50 of 18 nM [1] .

COC1=CC2=NC(N3CCC(N4CCCCC4)CC3)=NC(NC5CCCCCC5)=C2C=C1OC

-20°C,2°C to 8°C

12352200