C-021 [864289-85-0]

TargetMol Chemicals

C-021 [864289-85-0]

4

864289-85-0

Chemical

Research Use Only

C-021

C27H41N5O2

467.65

C 021 dihydrochloride is a potent CCR4 antagonist. C-021 (4-Quinazolinamine, 2-[1,4-bipiperidin]-1-yl-N-cycloheptyl-6,7-dimethoxy-) dihydrochloride potently inhibits functional chemotaxis in humans and mice with IC50s of 140 nM and 39 nM, respectively. It effectively prevents human CCL22-derived [35S]GTPgammaS from binding to the receptor (IC50: 18 nM).

3 years

N(C=1C2=C(N=C(N1)N3CCC(CC3)N4CCCCC4)C=C(OC)C(OC)=C2)C5CCCCCC5

-20°C

12352200