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C-021 dihydrochloride [1784252-84-1]

C-021 dihydrochloride [1784252-84-1]

T10639
TargetMol Chemicals
CAS Number1784252-84-1
Product group Chemicals
Estimated Purity98.51%
Molecular Weight540.57
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    C-021 dihydrochloride [1784252-84-1]
  • Delivery Days Customer
    9
  • CAS Number
    1784252-84-1
  • Certification
    Research Use Only
  • Chemical Name
    C-021 dihydrochloride
  • Estimated Purity
    98.51%
  • Molecular Formula
    C27H43Cl2N5O2
  • Molecular Weight
    540.57
  • Scientific Description
    C-021 dihydrochloride is a potent CCR4 antagonist that effectively inhibits functional chemotaxis in humans and mice, with IC50 values of 140 nM and 39 nM, respectively.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.Cl.COc1cc2nc(nc(NC3CCCCCC3)c2cc1OC)N1CCC(CC1)N1CCCCC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • McMillin M, Frampton G, Thompson M, et al. Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline. J Neuroinflammation. 2014,11:121. doi: 10.1186/1742-2094-11-121
    Read this paper

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