c-Fos antibody [2G9C3]

GeneTex

c-Fos antibody [2G9C3]

9

Reacts with both cellular and viral forms, will detect both the 55 kDa and 62 kDa c-fos and v-fos proteins, but does not react with the 39 kDa jun protein.

Not suitable for IHC frozen or parraffin-embedded sections. For ICC: Use at a concentration of 2.5 - 5.0 microg/ml. For WB: Use at a concentration of 2.5 - 5.0 microg/ml. Detects bands of approximately 55 and 62 kDa. Optimal dilutions/concentrations should be determined by the researcher.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

2G9C3

0.2 mg/ml

Unconjugated

FOS

Fos proto-oncogene, AP-1 transcription factor subunit

activator protein 1; AP-1; cellular oncogene c-fos; C-FOS; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS); FBJ murine osteosarcoma viral oncogene homolog; Fos proto-oncogene, AP-1 trancription factor subunit; G0/G1 switch regulatory protein 7; p55; proto-oncogene c-Fos

Mouse

IgG2a

Proto-oncogene c-Fos

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]

Human, Mouse, Rat

2°C to 8°C

12352203