c-Kit antibody [ACK2]
GTX01469
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetKit
Overview
- SupplierGeneTex
- Product Namec-Kit antibody [ACK2]
- Delivery Days Customer9
- Application Supplier Note*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDACK2
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID16590
- Target nameKit
- Target descriptionKIT proto-oncogene receptor tyrosine kinase
- Target synonymsBs, CD117, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, SCO1, SCO5, SOW3, Ssm, Tr-kit, W, c-KIT, mast/stem cell growth factor receptor Kit, Dominant white spotting, SCFR, Steel Factor Receptor, belly-spot, c-kit proto-oncogene protein, dominant spotting, kit oncogene, proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, spotted sterile male, tyrosine-protein kinase Kit
- HostRat
- IsotypeIgG2b
- Protein IDP05532
- Protein NameMast/stem cell growth factor receptor Kit
- Scientific DescriptionThe c-Kit proto-oncogene is the cellular homolog of the transforming gene of a feline retrovirus (v-Kit). The c-kit protein includes characteristics of a protein kinase transmembrane receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Launay JM, Hervé P, Callebert J, et al. Serotonin 5-HT2B receptors are required for bone-marrow contribution to pulmonary arterial hypertension. Blood. 2012,119(7):1772-80. doi: 10.1182/blood-2011-06-358374Read this paper
- Tang X, Tian L, Esteso G, et al. Leukocyte-associated Ig-like receptor-1-deficient mice have an altered immune cell phenotype. J Immunol. 2012,188(2):548-58. doi: 10.4049/jimmunol.1102044Read this paper
- Stanich JE, Gibbons SJ, Eisenman ST, et al. Ano1 as a regulator of proliferation. Am J Physiol Gastrointest Liver Physiol. 2011,301(6):G1044-51. doi: 10.1152/ajpgi.00196.2011Read this paper
- Mark-Kappeler CJ, Sen N, Lukefahr A, et al. Inhibition of ovarian KIT phosphorylation by the ovotoxicant 4-vinylcyclohexene diepoxide in rats. Biol Reprod. 2011,85(4):755-62. doi: 10.1095/biolreprod.111.092742Read this paper
- Kim MH, Granick JL, Kwok C, et al. Neutrophil survival and c-kit(+)-progenitor proliferation in Staphylococcus aureus-infected skin wounds promote resolution. Blood. 2011,117(12):3343-52. doi: 10.1182/blood-2010-07-296970Read this paper
- Fiorina P, Jurewicz M, Vergani A, et al. Targeting the CXCR4-CXCL12 axis mobilizes autologous hematopoietic stem cells and prolongs islet allograft survival via programmed death ligand 1. J Immunol. 2011,186(1):121-31. doi: 10.4049/jimmunol.1000799Read this paper
- Carlsson IB, Laitinen MP, Scott JE, et al. Kit ligand and c-Kit are expressed during early human ovarian follicular development and their interaction is required for the survival of follicles in long-term culture. Reproduction. 2006,131(4):641-9.Read this paper
![FACS analysis of mouse C57Bl/6 bone marrow cells using GTX01469-07 c-Kit antibody [ACK2] (APC). Right panel : co-stained with c-Kit antibody [ACK2] (APC) and Mouse CD45R antibody (FITC) Left panel : co-stained with isotype control and Mouse CD45R antibody (FITC) antibody amount : 0.06 microg (5 microl)](https://www.genetex.com/upload/website/prouct_img/normal/GTX01469-07/GTX01469-07_20200428_FACS21_w_23053121_176.webp)
![FACS analysis of mouse C57Bl/6 bone marrow cells using GTX01469-08 c-Kit antibody [ACK2] (PE). Right panel : co-stained with c-Kit antibody [ACK2] (PE) and Mouse CD45R antibody (APC) Left panel : co-stained with isotype control and Mouse CD45R antibody (APC) antibody amount : 0.06 microg (5 microl)](https://www.genetex.com/upload/website/prouct_img/normal/GTX01469-08/GTX01469-08_20200428_FACS113_w_23053121_385.webp)
![FACS analysis of mouse C57Bl/6 bone marrow cells using GTX01469-10 c-Kit antibody [ACK2] (PE-Cy7). Right panel : co-stained with c-Kit antibody [ACK2] (PE-Cy7) and Mouse CD45R antibody (FITC) Left panel : co-stained with isotype control and Mouse CD45R antibody (FITC) antibody amount : 0.5 microg (5 microl)](https://www.genetex.com/upload/website/prouct_img/normal/GTX01469-10/GTX01469-10_20200428_FACS146_w_23053121_424.webp)
![FACS analysis of mouse C57Bl/6 bone marrow cells using GTX01469-15 c-Kit antibody [ACK2] (APC-Cy7). Right panel : co-stained with c-Kit antibody [ACK2] (APC-Cy7) and Mouse CD45R antibody (violetFluor? 450) Left panel : co-stained with isotype control and Mouse CD45R antibody (violetFluor? 450) antibody amount : 0.25 microg (5 microl)](https://www.genetex.com/upload/website/prouct_img/normal/GTX01469-15/GTX01469-15_20200428_FACS47_w_23053121_212.webp)
