Bio-Connect

c-Kit antibody [ACK2]

GTX01469
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetKit
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Overview

  • Supplier
    GeneTex
  • Product Name
    c-Kit antibody [ACK2]
  • Delivery Days Customer
    9
  • Application Supplier Note
    *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    ACK2
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID16590
  • Target name
    Kit
  • Target description
    KIT proto-oncogene receptor tyrosine kinase
  • Target synonyms
    Bs, CD117, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, SCO1, SCO5, SOW3, Ssm, Tr-kit, W, c-KIT, mast/stem cell growth factor receptor Kit, Dominant white spotting, SCFR, Steel Factor Receptor, belly-spot, c-kit proto-oncogene protein, dominant spotting, kit oncogene, proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, spotted sterile male, tyrosine-protein kinase Kit
  • Host
    Rat
  • Isotype
    IgG2b
  • Protein IDP05532
  • Protein Name
    Mast/stem cell growth factor receptor Kit
  • Scientific Description
    The c-Kit proto-oncogene is the cellular homolog of the transforming gene of a feline retrovirus (v-Kit). The c-kit protein includes characteristics of a protein kinase transmembrane receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Launay JM, Hervé P, Callebert J, et al. Serotonin 5-HT2B receptors are required for bone-marrow contribution to pulmonary arterial hypertension. Blood. 2012,119(7):1772-80. doi: 10.1182/blood-2011-06-358374
    Read this paper
  • Tang X, Tian L, Esteso G, et al. Leukocyte-associated Ig-like receptor-1-deficient mice have an altered immune cell phenotype. J Immunol. 2012,188(2):548-58. doi: 10.4049/jimmunol.1102044
    Read this paper
  • Stanich JE, Gibbons SJ, Eisenman ST, et al. Ano1 as a regulator of proliferation. Am J Physiol Gastrointest Liver Physiol. 2011,301(6):G1044-51. doi: 10.1152/ajpgi.00196.2011
    Read this paper
  • Mark-Kappeler CJ, Sen N, Lukefahr A, et al. Inhibition of ovarian KIT phosphorylation by the ovotoxicant 4-vinylcyclohexene diepoxide in rats. Biol Reprod. 2011,85(4):755-62. doi: 10.1095/biolreprod.111.092742
    Read this paper
  • Kim MH, Granick JL, Kwok C, et al. Neutrophil survival and c-kit(+)-progenitor proliferation in Staphylococcus aureus-infected skin wounds promote resolution. Blood. 2011,117(12):3343-52. doi: 10.1182/blood-2010-07-296970
    Read this paper
  • Fiorina P, Jurewicz M, Vergani A, et al. Targeting the CXCR4-CXCL12 axis mobilizes autologous hematopoietic stem cells and prolongs islet allograft survival via programmed death ligand 1. J Immunol. 2011,186(1):121-31. doi: 10.4049/jimmunol.1000799
    Read this paper
  • Carlsson IB, Laitinen MP, Scott JE, et al. Kit ligand and c-Kit are expressed during early human ovarian follicular development and their interaction is required for the survival of follicles in long-term culture. Reproduction. 2006,131(4):641-9.
    Read this paper