ProductsBack/c-Kit antibody [ACK2] (PE-Cy7)

FACS analysis of mouse C57Bl/6 bone marrow cells using GTX01469-10 c-Kit antibody [ACK2] (PE-Cy7). Right panel : co-stained with c-Kit antibody [ACK2] (PE-Cy7) and Mouse CD45R antibody (FITC) Left panel : co-stained with isotype control and Mouse CD45R antibody (FITC) antibody amount : 0.5 microg (5 microl)

c-Kit antibody [ACK2] (PE-Cy7)

GTX01469-10

ApplicationsFlow Cytometry

Product group Antibodies

ReactivityMouse

TargetKit

Overview

Supplier
GeneTex
Product Name
c-Kit antibody [ACK2] (PE-Cy7)
Delivery Days Customer
9
Application Supplier Note
*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Flow Cytometry
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
ACK2
Concentration
0.2 mg/ml
Conjugate
Double Conjugated
Gene ID16590
Target name
Kit
Target description
KIT proto-oncogene receptor tyrosine kinase
Target synonyms
Bs, CD117, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, SCO1, SCO5, SOW3, Ssm, Tr-kit, W, c-KIT, mast/stem cell growth factor receptor Kit, Dominant white spotting, SCFR, Steel Factor Receptor, belly-spot, c-kit proto-oncogene protein, dominant spotting, kit oncogene, proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, spotted sterile male, tyrosine-protein kinase Kit
Host
Rat
Isotype
IgG2b
Protein IDP05532
Protein Name
Mast/stem cell growth factor receptor Kit
Scientific Description
The c-Kit proto-oncogene is the cellular homolog of the transforming gene of a feline retrovirus (v-Kit). The c-kit protein includes characteristics of a protein kinase transmembrane receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Reactivity
Mouse
Storage Instruction
2°C to 8°C
UNSPSC
12352203

References

Launay JM, Hervé P, Callebert J, et al. Serotonin 5-HT2B receptors are required for bone-marrow contribution to pulmonary arterial hypertension. Blood. 2012,119(7):1772-80. doi: 10.1182/blood-2011-06-358374
Read this paper
Tang X, Tian L, Esteso G, et al. Leukocyte-associated Ig-like receptor-1-deficient mice have an altered immune cell phenotype. J Immunol. 2012,188(2):548-58. doi: 10.4049/jimmunol.1102044
Read this paper
Stanich JE, Gibbons SJ, Eisenman ST, et al. Ano1 as a regulator of proliferation. Am J Physiol Gastrointest Liver Physiol. 2011,301(6):G1044-51. doi: 10.1152/ajpgi.00196.2011
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Mark-Kappeler CJ, Sen N, Lukefahr A, et al. Inhibition of ovarian KIT phosphorylation by the ovotoxicant 4-vinylcyclohexene diepoxide in rats. Biol Reprod. 2011,85(4):755-62. doi: 10.1095/biolreprod.111.092742
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Kim MH, Granick JL, Kwok C, et al. Neutrophil survival and c-kit(+)-progenitor proliferation in Staphylococcus aureus-infected skin wounds promote resolution. Blood. 2011,117(12):3343-52. doi: 10.1182/blood-2010-07-296970
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Fiorina P, Jurewicz M, Vergani A, et al. Targeting the CXCR4-CXCL12 axis mobilizes autologous hematopoietic stem cells and prolongs islet allograft survival via programmed death ligand 1. J Immunol. 2011,186(1):121-31. doi: 10.4049/jimmunol.1000799
Read this paper
Carlsson IB, Laitinen MP, Scott JE, et al. Kit ligand and c-Kit are expressed during early human ovarian follicular development and their interaction is required for the survival of follicles in long-term culture. Reproduction. 2006,131(4):641-9.
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c-Kit antibody [ACK2] (PE-Cy7)

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