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ProductsBack/c-Myc antibody

c-Myc antibody

GTX20056
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetMYC
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Overview

  • Supplier
    GeneTex
  • Product Name
    c-Myc antibody [9E11]
  • Delivery Days Customer
    9
  • Application Supplier Note
    Suggested working dilutions: Immunoprecipitation: 2 microg/mg protein lysate Western blotting: 1:500-1:1000. Optimal dilutions/concentrations should be determined by the end user
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Concentration
    0.7 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4609
  • Target name
    MYC
  • Target description
    MYC proto-oncogene, bHLH transcription factor
  • Target synonyms
    avian myelocytomatosis viral oncogene homolog; bHLHe39; class E basic helix-loop-helix protein 39; c-Myc; MRTL; myc proto-oncogene protein; MYCC; myc-related translation/localization regulatory factor; proto-oncogene c-Myc; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP01106
  • Protein Name
    Myc proto-oncogene protein
  • Scientific Description
    This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Interferon-induced transmembrane protein 3 is a type II transmembrane protein. Bailey CC et al., 2013 Nov 8, J Biol Chem
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  • Regulation of the yeast Ace2 transcription factor during the cell cycle. Sbia M et al., 2008 Apr 25, J Biol Chem
    Read more
  • Dephosphorylation and genome-wide association of Maf1 with Pol III-transcribed genes during repression. Roberts DN et al., 2006 Jun 9, Mol Cell
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  • High functional overlap between MluI cell-cycle box binding factor and Swi4/6 cell-cycle box binding factor in the G1/S transcriptional program in Saccharomyces cerevisiae. Bean JM et al., 2005 Sep, Genetics
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  • Interaction of the S-phase cyclin Clb5 with an RXL docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch. Wilmes GM et al., 2004 May 1, Genes Dev
    Read more