
The data was published in the journal PLoS One in 2013.
c-Myc antibody [9E10]
GTX20032
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetMYC
Overview
- SupplierGeneTex
- Product Namec-Myc antibody [9E10]
- Delivery Days Customer9
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- ConjugateUnconjugated
- Gene ID4609
- Target nameMYC
- Target descriptionMYC proto-oncogene, bHLH transcription factor
- Target synonymsMRTL, MYCC, bHLHe39, c-Myc, myc proto-oncogene protein, avian myelocytomatosis viral oncogene homolog, class E basic helix-loop-helix protein 39, myc-related translation/localization regulatory factor, proto-oncogene c-Myc, transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog
- HostMouse
- IsotypeIgG1
- Protein IDP01106
- Protein NameMyc proto-oncogene protein
- Scientific DescriptionThis gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC41116161
References
- Large-scale phenogenomic analysis of human cancers uncovers frequent alterations affecting SMC5/6 complex components in breast cancer.Read this paper
- Cauliflower mosaic virus P6 Dysfunctions Histone Deacetylase HD2C to Promote Virus Infection. Li S et al., 2021 Sep 1, CellsRead this paper
- CUL4-DDB1-CRBN E3 Ubiquitin Ligase Regulates Proteostasis of ClC-2 Chloride Channels: Implication for Aldosteronism and Leukodystrophy. Fu SJ et al., 2020 May 26, CellsRead this paper
- A nonsense mutant of the hepatitis B virus large S protein antagonizes multiple tumor suppressor pathways through c-Jun activation domain-binding protein1. Chiu SY et al., 2019, PLoS OneRead this paper
- Cdc48/VCP Promotes Chromosome Morphogenesis by Releasing Condensin from Self-Entrapment in Chromatin. Thattikota Y et al., 2018 Feb 15, Mol CellRead this paper
- Trichosanthin increases Granzyme B penetration into tumor cells by upregulation of CI-MPR on the cell surface. Li C et al., 2017 Apr 18, OncotargetRead this paper
- Fbxl18 targets LRRK2 for proteasomal degradation and attenuates cell toxicity. Ding X et al., 2017 Feb, Neurobiol DisRead this paper
- Src phosphorylation converts Mdm2 from a ubiquitinating to a neddylating E3 ligase. Batuello CN et al., 2015 Feb 10, Proc Natl Acad Sci U S ARead this paper
- Intracellular Theileria annulata promote invasive cell motility through kinase regulation of the host actin cytoskeleton. Ma M et al., 2014 Mar, PLoS PathogRead this paper


![Indirect ELISA analysis was performed by coating the plate with recombinant Multiple Tags Positive Control ( 6xHis-MBP-DDDDK-V5-HSV-HA-T7-Myc-S) (GTX130342-pro) (57.14-0.89 nM). Coated protein was probed with c-Myc antibody [9E10] (GTX20032) (1 μg/mL). Goat antibody Mouse IgG antibody (HRP) (1:10000) was used to detect the bound primary antibody. Indirect ELISA analysis was performed by coating the plate with recombinant Multiple Tags Positive Control ( 6xHis-MBP-DDDDK-V5-HSV-HA-T7-Myc-S) (GTX130342-pro) (57.14-0.89 nM). Coated protein was probed with c-Myc antibody [9E10] (GTX20032) (1 μg/mL). Goat antibody Mouse IgG antibody (HRP) (1:10000) was used to detect the bound primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX20032/GTX20032_82200350_20240621_ELISA_Indirect_24062501_888.webp)







