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The data was published in the journal PLoS One in 2013.
The data was published in the journal PLoS One in 2013.
The data was published in the journal PLoS One in 2013.

c-Myc antibody [9E10]

GTX20032
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetMYC
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Overview

  • Supplier
    GeneTex
  • Product Name
    c-Myc antibody [9E10]
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Conjugate
    Unconjugated
  • Gene ID4609
  • Target name
    MYC
  • Target description
    MYC proto-oncogene, bHLH transcription factor
  • Target synonyms
    MRTL, MYCC, bHLHe39, c-Myc, myc proto-oncogene protein, avian myelocytomatosis viral oncogene homolog, class E basic helix-loop-helix protein 39, myc-related translation/localization regulatory factor, proto-oncogene c-Myc, transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP01106
  • Protein Name
    Myc proto-oncogene protein
  • Scientific Description
    This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    41116161

References

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    Read this paper
  • Cauliflower mosaic virus P6 Dysfunctions Histone Deacetylase HD2C to Promote Virus Infection. Li S et al., 2021 Sep 1, Cells
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  • CUL4-DDB1-CRBN E3 Ubiquitin Ligase Regulates Proteostasis of ClC-2 Chloride Channels: Implication for Aldosteronism and Leukodystrophy. Fu SJ et al., 2020 May 26, Cells
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  • A nonsense mutant of the hepatitis B virus large S protein antagonizes multiple tumor suppressor pathways through c-Jun activation domain-binding protein1. Chiu SY et al., 2019, PLoS One
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  • Cdc48/VCP Promotes Chromosome Morphogenesis by Releasing Condensin from Self-Entrapment in Chromatin. Thattikota Y et al., 2018 Feb 15, Mol Cell
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  • Trichosanthin increases Granzyme B penetration into tumor cells by upregulation of CI-MPR on the cell surface. Li C et al., 2017 Apr 18, Oncotarget
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  • Fbxl18 targets LRRK2 for proteasomal degradation and attenuates cell toxicity. Ding X et al., 2017 Feb, Neurobiol Dis
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  • Src phosphorylation converts Mdm2 from a ubiquitinating to a neddylating E3 ligase. Batuello CN et al., 2015 Feb 10, Proc Natl Acad Sci U S A
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  • Intracellular Theileria annulata promote invasive cell motility through kinase regulation of the host actin cytoskeleton. Ma M et al., 2014 Mar, PLoS Pathog
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