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ProductsBack/C3 / C3b antibody [C3], C-term

C3 / C3b antibody [C3], C-term

Research Use Only
GTX101316
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetC3
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Overview

  • Supplier
    GeneTex
  • Product Name
    C3 / C3b antibody [C3], C-term
  • Delivery Days Customer
    9
  • Antibody Specificity
    The mouse reactivity of this antibody is based on mouse IHC-P testing and may be not suitable for mouse WB assay.
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.08 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID718
  • Target name
    C3
  • Target description
    complement C3
  • Target synonyms
    acylation-stimulating protein cleavage product; AHUS5; ARMD9; ASP; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3b; complement C3; complement component 3; complement component C3a; complement component C3b; CPAMD1; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; prepro-C3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP01024
  • Protein Name
    Complement C3
  • Scientific Description
    Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Exposure to fluoride aggravates the impairment in learning and memory and neuropathological lesions in mice carrying the APP/PS1 double-transgenic mutation. Cao K et al., 2019 Apr 22, Alzheimers Res Ther
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  • Modulation of Iberian Ribbed Newt Complement Component C3 by Stressors Similar to those Encountered during a Stay Onboard the International Space Station. Gueguinou N et al., 2019 Mar 29, Int J Mol Sci
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  • Human skin mast cells express complement factors C3 and C5. Fukuoka Y et al., 2013 Aug 15, J Immunol
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  • Obesity-associated autoantibody production requires AIM to retain the immunoglobulin M immune complex on follicular dendritic cells. Arai S et al., 2013 Apr 25, Cell Rep
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  • Improved capillary electrophoresis method for the analysis of carbohydrate-deficient transferrin in human serum, avoiding interference by complement C3. Kuroda Y et al., 2013 Mar 25, J Pharm Biomed Anal
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