C3G antibody

GeneTex

C3G antibody

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1.23 mg/ml

Unconjugated

RAPGEF1

Rap guanine nucleotide exchange factor 1

C3G; CRK SH3-binding GNRP; GRF2; guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene); Rap guanine nucleotide exchange factor (GEF) 1; rap guanine nucleotide exchange factor 1

Rabbit

IgG

Rap guanine nucleotide exchange factor 1

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203