CA3 Antibody / Carbonic Anhydrase III

Biorbyt

CA3 Antibody / Carbonic Anhydrase III

10

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT IHC-P

Research Use Only

Monoclonal

CA3/7884

Unconjugated

CA3

carbonic anhydrase 3

CAIII, Car3, carbonic anhydrase 3, CA-III, HEL-S-167mP, carbonate dehydratase III, carbonic anhydrase III, muscle specific, carbonic anhydrase IIII, epididymis secretory sperm binding protein Li 167mP

Mouse

IgG2

Carbonic anhydrase 3

Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric juice. They show extensive diversity in distribution and in their subcellular localization. CA III (carbonic anhydrase III), also known as Car3 or CA3, is a 260 amino acid cytoplasmic protein that is specifically expressed in muscle. Belonging to the a-carbonic anhydrase family, CA III is activated by proton donors such as imidazole and dipeptide histidylhistidine, and is inhibited by coumarins and sulfonamide derivatives such as acetazolamide.

Human

-20°C

12352203