Cabozantinib malate
M4894
CAS Number1140909-48-3
Product group Chemicals
Estimated Purity>99.0%
Molecular Weight635.59
Overview
- SupplierAbMole BioScience
- Product NameCabozantinib malate
- Delivery Days Customer9
- CAS Number1140909-48-3
- Category SupplierChemical
- CertificationResearch Use Only
- Estimated Purity>99.0%
- Molecular FormulaC28H24FN3O5.C4H6O5
- Molecular Weight635.59
- Scientific DescriptionCabozantinib malate (XL184) is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively.
- SMILESCOC1=CC2=C(C=C1OC)C(=CC=N2)OC3=CC=C(NC(=O)C4(CC4)C(=O)NC5=CC=C(F)C=C5)C=C3.OC(CC(O)=O)C(O)=O
- UNSPSC12352200