Bio-Connect

Cabozantinib malate

M4894
AbMole BioScience
CAS Number1140909-48-3
Product group Chemicals
Estimated Purity>99.0%
Molecular Weight635.59
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Cabozantinib malate
  • Delivery Days Customer
    9
  • CAS Number
    1140909-48-3
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    >99.0%
  • Molecular Formula
    C28H24FN3O5.C4H6O5
  • Molecular Weight
    635.59
  • Scientific Description
    Cabozantinib malate (XL184) is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively.
  • SMILES
    COC1=CC2=C(C=C1OC)C(=CC=N2)OC3=CC=C(NC(=O)C4(CC4)C(=O)NC5=CC=C(F)C=C5)C=C3.OC(CC(O)=O)C(O)=O
  • UNSPSC
    12352200