Chemical Structure
Chemical Structure
Cabozantinib S-malate [1140909-48-3]
CDX-C0698
CAS Number1140909-48-3
Product group Chemicals
Estimated Purity>99%
Molecular Weight635.59
Overview
- SupplierChemodex
- Product NameCabozantinib S-malate [1140909-48-3]
- Delivery Days Customer10
- CAS Number1140909-48-3
- CertificationResearch Use Only
- Estimated Purity>99%
- Molecular FormulaC32H30FN3O10
- Molecular Weight635.59
- Scientific DescriptionChemical. CAS: 1140909-48-3. Formula: C32H30FN3O10. MW: 635.59. The s-malate salt form of Cabozantinib is very potent orally available inhibitor of multiple receptor tyrosine kinases (RTK), specifically MET and VEGFR2. It also inhibits KIT, FLT3, Tie-2, RET and AXL. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature, angiogenesis and extensive tumor cell apoptosis. - The s-malate salt form of Cabozantinib is very potent orally available inhibitor of multiple receptor tyrosine kinases (RTK), specifically MET and VEGFR2. It also inhibits KIT, FLT3, Tie-2, RET and AXL. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature, angiogenesis and extensive tumor cell apoptosis.
- SMILESO=C(C1(CC1)C(NC2=CC=C(F)C=C2)=O)NC(C=C3)=CC=C3OC4=CC=NC5=CC(OC)=C(OC)C=C54.O=C(O)C[C@H](O)C(O)=O
- Storage Instruction2°C to 8°C
- UNSPSC12352200