Calhex 231 (hydrochloride)

MedChem Express

Calhex 231 (hydrochloride) [2387505-78-2]

10

2387505-78-2

Research Use Only

99.81

C25H28Cl2N2O

443.41

Calhex 231 hydrochloride is a potent negative allosteric modulator that blocks (IC 50 = 0.39 microM) increases in [ 3 H]inositol phosphates elicited by activating the human wild-type CaSR transiently Ca 2+ -sensing receptor. Calhex 231 hydrochloride can be used in the study of traumatic hemorrhagic shock (THS) and diabetic cardiomyopathy (DCM) [1] .

O=C(N[C@@H]1[C@@H](N[C@@H](C2=C3C=CC=CC3=CC=C2)C)CCCC1)C4=CC=C(Cl)C=C4.[H]Cl

-20°C

12352200