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Calhex 231 hydrochloride [2387505-78-2]

Calhex 231 hydrochloride [2387505-78-2]

T10666
TargetMol Chemicals
CAS Number2387505-78-2
Product group Chemicals
Molecular Weight443.41
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Calhex 231 hydrochloride [2387505-78-2]
  • Delivery Days Customer
    14
  • CAS Number
    2387505-78-2
  • Certification
    Research Use Only
  • Chemical Name
    Calhex 231 hydrochloride
  • Molecular Formula
    C25H28Cl2N2O
  • Molecular Weight
    443.41
  • Scientific Description
    Calhex 231 hydrochloride is a CaSR inhibitor with potential for diabetic cardiomyopathy treatment; it blocks Ca2+-induced accumulation of [3H]inositol phosphate with an IC50 of 0.39 microM in HEK293 cells.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.C[C@@H](N[C@H]1CCCC[C@@H]1NC(=O)c1ccc(Cl)cc1)c1cccc2ccccc12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Yuan H, Xu J, Xu X, et al. Calhex(231) Alleviates High Glucose-Induced Myocardial Fibrosis via Inhibiting Itch-Ubiquitin Proteasome Pathway in Vitro. Biol Pharm Bull. 2019,42(8):1337-1344. doi: 10.1248/bpb.b19-00090
    Read this paper