Calnexin antibody [C3], C-term
GTX109669
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat, Sheep
TargetCANX
Overview
- SupplierGeneTex
- Product NameCalnexin antibody [C3], C-term
- Delivery Days Customer9
- Antibody SpecificityIP/MS validation was supported by references (PMID:30377396)
- Application Supplier NoteWB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.2 mg/ml
- ConjugateUnconjugated
- Gene ID821
- Target nameCANX
- Target descriptioncalnexin
- Target synonymscalnexin; CNX; epididymis secretory sperm binding protein; IP90; major histocompatibility complex class I antigen-binding protein p88; P90
- HostRabbit
- IsotypeIgG
- Protein IDP27824
- Protein NameCalnexin
- Scientific DescriptionThis gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat, Sheep
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Outcome of severely injured patients in a unique trauma system with 24/7 double trauma surgeon on-call service.Read more
- Exosomal long noncoding RNA MLETA1 promotes tumor progression and metastasis by regulating the miR-186-5p/EGFR and miR-497-5p/IGF1R axes in non-small cell lung cancer.Read more
- Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics.Read more
- Huntingtin exon 1 deletion does not alter the subcellular distribution of huntingtin and gene transcription in mice.Read more
- Circ_0006790 carried by bone marrow mesenchymal stem cell-derived exosomes regulates S100A11 DNA methylation through binding to CBX7 in pancreatic ductal adenocarcinoma. Gao G et al., 2022, Am J Cancer ResRead more
- Extracellular ATP is increased by release of ATP-loaded microparticles triggered by nutrient deprivation. Vultaggio-Poma V et al., 2022, TheranosticsRead more
- P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells. Pegoraro A et al., 2021 Nov 16, Cell Death DisRead more
- Thyroglobulin Interactome Profiling Defines Altered Proteostasis Topology Associated With Thyroid Dyshormonogenesis. Wright MT et al., 2021, Mol Cell ProteomicsRead more
- NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma. Hu W et al., 2021 Feb 8, JCI InsightRead more
- Comparative Multiplexed Interactomics of SARS-CoV-2 and Homologous Coronavirus Nonstructural Proteins Identifies Unique and Shared Host-Cell Dependencies. Davies JP et al., 2020 Dec 11, ACS Infect DisRead more