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Calnexin antibody [N3C2], Internal

GTX101676
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCANX
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Overview

  • Supplier
    GeneTex
  • Product Name
    Calnexin antibody [N3C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.16 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID821
  • Target name
    CANX
  • Target description
    calnexin
  • Target synonyms
    CNX, IP90, P90, calnexin, epididymis secretory sperm binding protein, major histocompatibility complex class I antigen-binding protein p88
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP27824
  • Protein Name
    Calnexin
  • Scientific Description
    This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • van de Wakker SI, van Oudheusden J, Mol EA, et al. Influence of short term storage conditions, concentration methodsand excipients on extracellular vesicle recovery and function. Eur J Pharm Biopharm. 2022,170:59-69. doi: 10.1016/j.ejpb.2021.11.012
    Read this paper
  • Wijenayake S, Eisha S, Tawhidi Z, et al. Comparison of methods for pre-processing, exosome isolation, and RNA extraction in unpasteurized bovine and human milk. PLoS One. 2021,16(9):e0257633. doi: 10.1371/journal.pone.0257633
    Read this paper
  • de Jong OG, Murphy DE, Mäger I, et al. A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA. Nat Commun. 2020,11(1):1113. doi: 10.1038/s41467-020-14977-8
    Read this paper
  • van den Hoogen P, de Jager SCA, Mol EA, et al. Potential of mesenchymal- and cardiac progenitor cells for therapeutic targeting of B-cells and antibody responses in end-stage heart failure. PLoS One. 2019,14(12):e0227283. doi: 10.1371/journal.pone.0227283
    Read this paper
  • Ilahibaks NF, Lei Z, Mol EA, et al. Biofabrication of Cell-Derived Nanovesicles: A Potential Alternative to Extracellular Vesicles for Regenerative Medicine. Cells. 2019,8(12). doi: 10.3390/cells8121509
    Read this paper
  • Costa Verdera H, Gitz-Francois JJ, Schiffelers RM, et al. Cellular uptake of extracellular vesicles is mediated by clathrin-independent endocytosis and macropinocytosis. J Control Release. 2017,266:100-108. doi: 10.1016/j.jconrel.2017.09.019
    Read this paper
  • Sever L, Vo NT, Bols NC, et al. Rainbow trout (Oncorhynchus mykiss) contain two calnexin genes which encode distinct proteins. Dev Comp Immunol. 2014,42(2):211-9. doi: 10.1016/j.dci.2013.09.005
    Read this paper