Bio-Connect

Calnexin antibody [N3C2], Internal

GTX101676
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCANX
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Overview

  • Supplier
    GeneTex
  • Product Name
    Calnexin antibody [N3C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.16 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID821
  • Target name
    CANX
  • Target description
    calnexin
  • Target synonyms
    calnexin; CNX; epididymis secretory sperm binding protein; IP90; major histocompatibility complex class I antigen-binding protein p88; P90
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP27824
  • Protein Name
    Calnexin
  • Scientific Description
    This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Influence of short term storage conditions, concentration methodsand excipients on extracellular vesicle recovery and function. van de Wakker SI et al., 2022 Jan, Eur J Pharm Biopharm
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  • Comparison of methods for pre-processing, exosome isolation, and RNA extraction in unpasteurized bovine and human milk. Wijenayake S et al., 2021, PLoS One
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  • A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA. de Jong OG et al., 2020 Feb 28, Nat Commun
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  • Potential of mesenchymal- and cardiac progenitor cells for therapeutic targeting of B-cells and antibody responses in end-stage heart failure. van den Hoogen P et al., 2019, PLoS One
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  • Biofabrication of Cell-Derived Nanovesicles: A Potential Alternative to Extracellular Vesicles for Regenerative Medicine. Ilahibaks NF et al., 2019 Nov 25, Cells
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  • Cellular uptake of extracellular vesicles is mediated by clathrin-independent endocytosis and macropinocytosis. Costa Verdera H et al., 2017 Nov 28, J Control Release
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  • Rainbow trout (Oncorhynchus mykiss) contain two calnexin genes which encode distinct proteins. Sever L et al., 2014 Feb, Dev Comp Immunol
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