Calnexin antibody [N3C2], Internal
GTX101676
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCANX
Overview
- SupplierGeneTex
- Product NameCalnexin antibody [N3C2], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.16 mg/ml
- ConjugateUnconjugated
- Gene ID821
- Target nameCANX
- Target descriptioncalnexin
- Target synonymsCNX, IP90, P90, calnexin, epididymis secretory sperm binding protein, major histocompatibility complex class I antigen-binding protein p88
- HostRabbit
- IsotypeIgG
- Protein IDP27824
- Protein NameCalnexin
- Scientific DescriptionThis gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- van de Wakker SI, van Oudheusden J, Mol EA, et al. Influence of short term storage conditions, concentration methodsand excipients on extracellular vesicle recovery and function. Eur J Pharm Biopharm. 2022,170:59-69. doi: 10.1016/j.ejpb.2021.11.012Read this paper
- Wijenayake S, Eisha S, Tawhidi Z, et al. Comparison of methods for pre-processing, exosome isolation, and RNA extraction in unpasteurized bovine and human milk. PLoS One. 2021,16(9):e0257633. doi: 10.1371/journal.pone.0257633Read this paper
- de Jong OG, Murphy DE, Mäger I, et al. A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA. Nat Commun. 2020,11(1):1113. doi: 10.1038/s41467-020-14977-8Read this paper
- van den Hoogen P, de Jager SCA, Mol EA, et al. Potential of mesenchymal- and cardiac progenitor cells for therapeutic targeting of B-cells and antibody responses in end-stage heart failure. PLoS One. 2019,14(12):e0227283. doi: 10.1371/journal.pone.0227283Read this paper
- Ilahibaks NF, Lei Z, Mol EA, et al. Biofabrication of Cell-Derived Nanovesicles: A Potential Alternative to Extracellular Vesicles for Regenerative Medicine. Cells. 2019,8(12). doi: 10.3390/cells8121509Read this paper
- Costa Verdera H, Gitz-Francois JJ, Schiffelers RM, et al. Cellular uptake of extracellular vesicles is mediated by clathrin-independent endocytosis and macropinocytosis. J Control Release. 2017,266:100-108. doi: 10.1016/j.jconrel.2017.09.019Read this paper
- Sever L, Vo NT, Bols NC, et al. Rainbow trout (Oncorhynchus mykiss) contain two calnexin genes which encode distinct proteins. Dev Comp Immunol. 2014,42(2):211-9. doi: 10.1016/j.dci.2013.09.005Read this paper
![IHC-P analysis of human renal cell carcinoma tissue using GTX17859 Calnexin antibody [CANX/1543].](https://www.genetex.com/upload/website/prouct_img/normal/GTX17859/GTX17859_20200115_IHC-P_1063_w_23060620_155.webp)


![ICC/IF analysis of HeLa cells using GTX83045 Calnexin antibody [3H4A7]. Green : Calnexin Red : Actin filament](https://www.genetex.com/upload/website/prouct_img/normal/GTX83045/GTX83045_20170912_ICCIF_w_23061322_711.webp)
![ICC/IF analysis of HeLa cells using GTX34446 Calnexin antibody [CANX/1541]. Green : Primary antibody Red : nucleus](https://www.genetex.com/upload/website/prouct_img/normal/GTX34446/GTX34446_20200115_ICC-IF_195_w_23060801_883.webp)


