Calpain 3 antibody [Calp3d/2C4]

GeneTex

Calpain 3 antibody [Calp3d/2C4]

9

This antibody reacts with full-size calpain 3 (94 kD) plus an additional fragment at 30 kD in human skeletal muscle. A band of 94 kD is seen with rabbit and dog muscle while extracts of hamster muscle show reactivity with the 94 kD band and a larger speci

WB: 1:25-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

Calp3d/2C4

Unconjugated

CAPN3

calpain 3

calpain p94, large [catalytic] subunit; calpain, large polypeptide L3; calpain-3; CANP3; CANPL3; LGMD2; LGMD2A; LGMDD4; LGMDR1; muscle-specific calcium-activated neutral protease 3 large subunit; nCL-1; new calpain 1; p94

Mouse

IgG2b

Calpain-3

Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008]

Canine, Hamster, Human, Rabbit, Rat

-20°C or -80°C,2°C to 8°C

12352203