Bio-Connect

Calphostin C [121263-19-2]

HY-105416
MedChem Express
CAS Number121263-19-2
Product group Chemicals
Estimated Purity99.00
Molecular Weight790.76
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Calphostin C [121263-19-2]
  • Delivery Days Customer
    10
  • CAS Number
    121263-19-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.00
  • Molecular Formula
    C44H38O14
  • Molecular Weight
    790.76
  • Scientific Description
    Calphostin C is a highly selective PKC inhibitor (IC50=0.05 microM) and tumor apoptosis inducer. Calphostin C competitively binds to PKC and inhibits PKC-mediated phosphorylation signal transduction. Calphostin C restores Na+/K+ ATPase activity in the sciatic nerve of diabetic mice and improves neuropathy. Calphostin C can be used in the study of anti-tumor and diabetic complications[1][2][3].
  • SMILES
    O=C(O[C@@H](CC1=C(C(C2=C(C=C(C(C3=C4C5=C(O)C=C3OC)=C2C1=C4C(C[C@@H](C)OC(C6=CC=CC=C6)=O)=C(OC)C5=O)OC)O)=O)OC)C)OC7=CC=C(C=C7)O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200