Calreticulin (human) (rec.) (His)

AdipoGen Life Sciences

Calreticulin (human) (rec.) (His)

10

Research Use Only

0.2 mg/ml

>90%

CALR

calreticulin

CALR1, CRT, HEL-S-99n, RO, SSA, cC1qR, calreticulin, CRP55, ERp60, HACBP, Sicca syndrome antigen A (autoantigen Ro; calreticulin), calregulin, endoplasmic reticulum resident protein 60, epididymis secretory sperm binding protein Li 99n, grp60

Calreticulin

Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the calreticulin/calnexin cycle that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumor cells, increasing phagocytosis. - Protein. Human calreticulin (aa18-417) is fused at the C-terminus to a His-tag. Source: E. coli. Endotoxin content: 90% (SDS-PAGE). Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the calreticulin/calnexin cycle that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumor cells, increasing phagocytosis.

-20°C,2°C to 8°C

41116100

Human