CaMKII delta antibody
GTX111401
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rabbit, Rat, Zebra Fish
TargetCAMK2D
Overview
- SupplierGeneTex
- Product NameCaMKII delta antibody
- Delivery Days Customer9
- Antibody SpecificityCross-reactivity may occur with other CaM kinase II subunits.
- Application Supplier NoteWB: 1:500-1:50000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.62 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID817
- Target nameCAMK2D
- Target descriptioncalcium/calmodulin dependent protein kinase II delta
- Target synonymscalcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase type II delta chain; calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II delta subunit; CAMKD; CaMK-II delta subunit; CaM-kinase II delta chain
- HostRabbit
- IsotypeIgG
- Protein IDQ13557
- Protein NameCalcium/calmodulin-dependent protein kinase type II subunit delta
- Scientific DescriptionThe product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.
- ReactivityHuman, Mouse, Rabbit, Rat, Zebra Fish
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- CaMKII-delta9 Induces Cardiomyocyte Death to Promote Cardiomyopathy and Heart Failure. Zhang M et al., 2021, Front Cardiovasc MedRead more
- Fibroblast Growth Factor 23 Stimulates Cardiac Fibroblast Activity through Phospholipase C-Mediated Calcium Signaling. Lee TW et al., 2021 Dec 23, Int J Mol SciRead more
- WWP1 Deficiency Alleviates Cardiac Remodeling Induced by Simulated Microgravity. Zhong G et al., 2021, Front Cell Dev BiolRead more
- The mitochondrial calcium uniporter promotes arrhythmias caused by high-fat diet. Joseph LC et al., 2021 Sep 8, Sci RepRead more
- Klotho modulates electrical activity and calcium homeostasis in pulmonary vein cardiomyocytes via PI3K/Akt signalling. Hung Y et al., 2020 Jul 1, EuropaceRead more
- Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity. Liu C et al., 2020 Mar, Cell ProlifRead more
- Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy. Himelman E et al., 2020 Apr 1, J Clin InvestRead more
- CaMKII-delta9 promotes cardiomyopathy through disrupting UBE2T-dependent DNA repair. Zhang M et al., 2019 Sep, Nat Cell BiolRead more
- Ca2+/Calmodulin-dependent kinase II delta B is essential for cardiomyocyte hypertrophy and complement gene expression after LPS and HSP60 stimulation in vitro. Cruz Junho CV et al., 2019, Braz J Med Biol ResRead more
- TMCO1-mediated Ca2+ leak underlies osteoblast functions via CaMKII signaling. Li J et al., 2019 Apr 8, Nat CommunRead more