CaMKII delta antibody
GTX111401
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCAMK2D
Overview
- SupplierGeneTex
- Product NameCaMKII delta antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:50000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.66 mg/ml
- ConjugateUnconjugated
- Gene ID817
- Target nameCAMK2D
- Target descriptioncalcium/calmodulin dependent protein kinase II delta
- Target synonymsCAMKD, calcium/calmodulin-dependent protein kinase type II subunit delta, CaM kinase II delta subunit, CaM-kinase II delta chain, CaMK-II delta subunit, calcium/calmodulin-dependent protein kinase (CaM kinase) II delta, calcium/calmodulin-dependent protein kinase type II delta chain
- HostRabbit
- IsotypeIgG
- Protein IDQ13557
- Protein NameCalcium/calmodulin-dependent protein kinase type II subunit delta
- Scientific DescriptionThe product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
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- Rocco-Machado N, Lai L, Kim G, et al. Oxidative stress-induced autonomous activation of the calcium/calmodulin-dependent kinase II involves disulfide formation in the regulatory domain. J Biol Chem. 2022,298(11):102579. doi: 10.1016/j.jbc.2022.102579Read this paper
- Zhang M, Zhang J, Zhang W, et al. CaMKII-δ9 Induces Cardiomyocyte Death to Promote Cardiomyopathy and Heart Failure. Front Cardiovasc Med. 2021,8:820416. doi: 10.3389/fcvm.2021.820416Read this paper
- Lee TW, Chung CC, Lee TI, et al. Fibroblast Growth Factor 23 Stimulates Cardiac Fibroblast Activity through Phospholipase C-Mediated Calcium Signaling. Int J Mol Sci. 2021,23(1). doi: 10.3390/ijms23010166Read this paper
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- Joseph LC, Reyes MV, Homan EA, et al. The mitochondrial calcium uniporter promotes arrhythmias caused by high-fat diet. Sci Rep. 2021,11(1):17808. doi: 10.1038/s41598-021-97449-3Read this paper
- Hung Y, Chen YC, Huang SY, et al. Klotho modulates electrical activity and calcium homeostasis in pulmonary vein cardiomyocytes via PI3K/Akt signalling. Europace. 2020,22(7):1132-1141. doi: 10.1093/europace/euaa100Read this paper
- Liu C, Zhong G, Zhou Y, et al. Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity. Cell Prolif. 2020,53(3):e12783. doi: 10.1111/cpr.12783Read this paper
- Himelman E, Lillo MA, Nouet J, et al. Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy. J Clin Invest. 2020,130(4):1713-1727. doi: 10.1172/JCI128190Read this paper





