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CaMKII delta antibody

Research Use Only
GTX111401
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rabbit, Rat, Zebra Fish
TargetCAMK2D
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Overview

  • Supplier
    GeneTex
  • Product Name
    CaMKII delta antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    Cross-reactivity may occur with other CaM kinase II subunits.
  • Application Supplier Note
    WB: 1:500-1:50000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.62 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID817
  • Target name
    CAMK2D
  • Target description
    calcium/calmodulin dependent protein kinase II delta
  • Target synonyms
    calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase type II delta chain; calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II delta subunit; CAMKD; CaMK-II delta subunit; CaM-kinase II delta chain
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13557
  • Protein Name
    Calcium/calmodulin-dependent protein kinase type II subunit delta
  • Scientific Description
    The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.
  • Reactivity
    Human, Mouse, Rabbit, Rat, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • CaMKII-delta9 Induces Cardiomyocyte Death to Promote Cardiomyopathy and Heart Failure. Zhang M et al., 2021, Front Cardiovasc Med
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  • Fibroblast Growth Factor 23 Stimulates Cardiac Fibroblast Activity through Phospholipase C-Mediated Calcium Signaling. Lee TW et al., 2021 Dec 23, Int J Mol Sci
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  • WWP1 Deficiency Alleviates Cardiac Remodeling Induced by Simulated Microgravity. Zhong G et al., 2021, Front Cell Dev Biol
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  • The mitochondrial calcium uniporter promotes arrhythmias caused by high-fat diet. Joseph LC et al., 2021 Sep 8, Sci Rep
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  • Klotho modulates electrical activity and calcium homeostasis in pulmonary vein cardiomyocytes via PI3K/Akt signalling. Hung Y et al., 2020 Jul 1, Europace
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  • Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity. Liu C et al., 2020 Mar, Cell Prolif
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  • Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy. Himelman E et al., 2020 Apr 1, J Clin Invest
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  • CaMKII-delta9 promotes cardiomyopathy through disrupting UBE2T-dependent DNA repair. Zhang M et al., 2019 Sep, Nat Cell Biol
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  • Ca2+/Calmodulin-dependent kinase II delta B is essential for cardiomyocyte hypertrophy and complement gene expression after LPS and HSP60 stimulation in vitro. Cruz Junho CV et al., 2019, Braz J Med Biol Res
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  • TMCO1-mediated Ca2+ leak underlies osteoblast functions via CaMKII signaling. Li J et al., 2019 Apr 8, Nat Commun
    Read more