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Cardiac Troponin I antibody [N1C3]

Research Use Only
GTX109331
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTNNI3
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cardiac Troponin I antibody [N1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.05 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID7137
  • Target name
    TNNI3
  • Target description
    troponin I3, cardiac type
  • Target synonyms
    cardiomyopathy, dilated 2A (autosomal recessive); CMD1FF; CMD2A; CMH7; cTnI; RCM1; TNNC1; troponin I type 3 (cardiac); troponin I, cardiac muscle
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP19429
  • Protein Name
    Troponin I, cardiac muscle
  • Scientific Description
    Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • A Two-Electrode, Double-Pulsed Sensor Readout Circuit for Cardiac Troponin I Measurement. Shan SS et al., 2020 Dec, IEEE Trans Biomed Circuits Syst
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  • Electrical stimulation applied during differentiation drives the hiPSC-CMs towards a mature cardiac conduction-like cells. Crestani T et al., 2020 Dec 10, Biochem Biophys Res Commun
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