WB analysis of untreated or etoposide-treated Jurkat cell lysate using GTX18029 Caspase 2 antibody [4i13(C2)].
WB analysis of untreated or etoposide-treated Jurkat cell lysate using GTX18029 Caspase 2 antibody [4i13(C2)].
Caspase 2 antibody [4i13(C2)]
GTX18029
Overview
- SupplierGeneTex
- Product NameCaspase 2 antibody [4i13(C2)] - Orthogonal Validated
- Delivery Days Customer9
- Antibody SpecificityRecognizes endogenous levels of human procaspase-2 at ~48kD as well as its 14 and 12kD cleaved fragments.
- Application Supplier NoteWB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID4i13(C2)
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID835
- Target nameCASP2
- Target descriptioncaspase 2
- Target synonymsCASP-2; caspase 2 apoptosis-related cysteine peptidase; caspase-2; ICH1; NEDD2; NEDD-2; neural precursor cell expressed developmentally down-regulated protein 2; PPP1R57; protease ICH-1; protein phosphatase 1, regulatory subunit 57
- HostMouse
- IsotypeIgG1
- Protein IDP42575
- Protein NameCaspase-2
- Scientific DescriptionThis gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimers disease, Huntingtons disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203