Caspase 2 antibody [4i13(C2)] - Orthogonal Validated

GeneTex

Caspase 2 antibody [4i13(C2)] - Orthogonal Validated

9

Recognizes endogenous levels of human procaspase-2 at ~48kD as well as its 14 and 12kD cleaved fragments.

Western Blot, ELISA

Research Use Only

Monoclonal

4i13(C2)

Unconjugated

CASP2

caspase 2

CASP-2; caspase 2 apoptosis-related cysteine peptidase; caspase-2; ICH1; NEDD2; NEDD-2; neural precursor cell expressed developmentally down-regulated protein 2; PPP1R57; protease ICH-1; protein phosphatase 1, regulatory subunit 57

Mouse

IgG1

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimers disease, Huntingtons disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Human

2°C to 8°C,-20°C or -80°C

12352203