Caspase 4 antibody, Internal

GeneTex

Caspase 4 antibody, Internal

9

WB: 0.3-1microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

CASP4

caspase 4

ICE(rel)II, ICEREL-II, ICH-2, Mih1, Mih1/TX, TX, caspase-4, CASP-4, ICE and Ced-3 homolog 2, ICE(rel)-II, apoptotic cysteine protease Mih1/TX, caspase 4, apoptosis-related cysteine peptidase, caspase 4, apoptosis-related cysteine protease, protease ICH-2, protease TX

Goat

IgG

Caspase-4

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203