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ICC/IF analysis of NIH3T3 cells using GTX01098 Caspase 6 antibody [GT1155]. Orange: Primary antibody Blue: DAPI
ICC/IF analysis of NIH3T3 cells using GTX01098 Caspase 6 antibody [GT1155]. Orange: Primary antibody Blue: DAPI
ICC/IF analysis of NIH3T3 cells using GTX01098 Caspase 6 antibody [GT1155]. Orange: Primary antibody Blue: DAPI

Caspase 6 antibody [GT1155]

GTX01098
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetCASP6
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Overview

  • Supplier
    GeneTex
  • Product Name
    Caspase 6 antibody [GT1155]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GT1155
  • Conjugate
    Unconjugated
  • Gene ID839
  • Target name
    CASP6
  • Target description
    caspase 6
  • Target synonyms
    CSP-6, MCH2, caspase-6, caspase-6, apoptotic protease MCH-2, caspase 6, apoptosis-related cysteine peptidase, caspase 6, apoptosis-related cysteine protease, mammalian Ced-3 homologue 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP55212
  • Protein Name
    Caspase-6
  • Scientific Description
    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Lin YC, Wang JC, Wu MS, et al. Nifedipine Exacerbates Lipogenesis in the Kidney via KIM-1, CD36, and SREBP Upregulation: Implications from an Animal Model for Human Study. Int J Mol Sci. 2020,21(12). doi: 10.3390/ijms21124359
    Read this paper
  • Lin YC, Wu MS, Lin YF, et al. Nifedipine Modulates Renal Lipogenesis via the AMPK-SREBP Transcriptional Pathway. Int J Mol Sci. 2019,20(7). doi: 10.3390/ijms20071570
    Read this paper

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