Immunohistochemistry of paraffin-embedded Rat heart using CAST Polyclonal Antibody at dilution of 1:100 (40x lens).
CAST Polyclonal Antibody
E-AB-63243
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCAST Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
- UNSPSC12352203