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Cathepsin D antibody [N2C2], Internal

GTX112847
GeneTex
ApplicationsWestern Blot
Product group Antibodies
TargetCTSD
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cathepsin D antibody [N2C2], Internal
  • Delivery Days Customer
    9
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.02 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1509
  • Target name
    CTSD
  • Target description
    cathepsin D
  • Target synonyms
    CLN10, CPSD, HEL-S-130P, cathepsin D, ceroid-lipofuscinosis, neuronal 10, epididymis secretory sperm binding protein Li 130P, lysosomal aspartyl peptidase, lysosomal aspartyl protease
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP07339
  • Protein Name
    Cathepsin D
  • Scientific Description
    This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Brandi J, Dalla Pozza E, Dando I, et al. Secretome protein signature of human pancreatic cancer stem-like cells. J Proteomics. 2016,136:1-12. doi: 10.1016/j.jprot.2016.01.017
    Read this paper
  • Hung TM, Yuan RH, Huang WP, et al. Increased Autophagy Markers Are Associated with Ductular Reaction during the Development of Cirrhosis. Am J Pathol. 2015,185(9):2454-67. doi: 10.1016/j.ajpath.2015.05.010
    Read this paper