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Cathepsin D antibody [N2C2], Internal

Research Use Only
GTX112847
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetCTSD
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cathepsin D antibody [N2C2], Internal
  • Delivery Days Customer
    9
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.02 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1509
  • Target name
    CTSD
  • Target description
    cathepsin D
  • Target synonyms
    cathepsin D; ceroid-lipofuscinosis, neuronal 10; CLN10; CPSD; epididymis secretory sperm binding protein Li 130P; HEL-S-130P; lysosomal aspartyl peptidase; lysosomal aspartyl protease
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Secretome protein signature of human pancreatic cancer stem-like cells. Brandi J et al., 2016 Mar 16, J Proteomics
    Read more
  • Increased Autophagy Markers Are Associated with Ductular Reaction during the Development of Cirrhosis. Hung TM et al., 2015 Sep, Am J Pathol
    Read more