CBL antibody [C2C3], C-term

GeneTex

CBL antibody [C2C3], C-term

9

Research Use Only

1 mg/ml

IgG

The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq]

2°C to 8°C,-20°C

12352203