CBR-470-1

Biorbyt

CBR-470-1 [2416095-06-0]

10

2416095-06-0

Research Use Only

C14H20CLNO4S2

365.8959

CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP+-induced cytotoxicity through activation of the Keap1-Nrf2 cascade.

ClC1C([H])=C([H])C(=C([H])C=1[H])S([C@@]1([H])C([H])([H])S(C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])(=O)=O)(=O)=O

12352200