CBR-470-1 [2416095-06-0]

TargetMol Chemicals

CBR-470-1 [2416095-06-0]

10

2416095-06-0

Chemical

Research Use Only

CBR-470-1

98.03%

C14H20ClNO4S2

365.9

CBR-470-1 is a potent inhibitor of glycolytic phosphoglycerate kinase 1 (PGK1) that activates NRF2 by increasing methylglyoxal levels. CBR-470-1 is a non-covalent Nrf2 activator with neuroprotective activity that protects SH-SY5Y neuronal cells from MPP+-induced cytotoxicity by activating the Keap1-Nrf2 cascade. cytotoxicity induced by MPP+.

3 years

S(=O)(=O)([C@@H]1[C@@H](NCC(C)C)CS(=O)(=O)C1)C2=CC=C(Cl)C=C2

-20°C

12352200