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CBR-5884

HY-100012
MedChem Express
CAS Number681159-27-3
DownloadMSDS
Product group Chemicals
Estimated Purity99.02
Molecular Weight336.39
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CBR-5884 [681159-27-3]
  • Delivery Days Customer
    10
  • CAS Number
    681159-27-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.02
  • Molecular Formula
    C14H12N2O4S2
  • Molecular Weight
    336.39
  • Scientific Description
    CBR-5884 is an active, selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC 50 of 33 microM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis [1] .
  • SMILES
    O=C(C1=C(C)C(SC#N)=C(NC(C2=CC=CO2)=O)S1)OCC
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200