CC-90005 [1799574-70-1]

MedChem Express

CC-90005 [1799574-70-1]

5

1799574-70-1

Research Use Only

99.67

C21H27F2N7O2

447.48

CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-theta (PKC-theta), with an IC50 of 8 nM. CC-90005 shows selectivity for PKC-theta over PKC-delta (IC50=4440 nM). CC-90005 can inhibit T cell activation by inhibiting IL-2 expression[1].

N#CC1=CN=C(NCC2=CN=CN=C2OCC(F)(F)C)N=C1N[C@H]3CC(C)(C)[C@@H](O)CC3

-20°C,2°C to 8°C

12352200