CCL4 Polyclonal Antibody

Elabscience

CCL4 Polyclonal Antibody

12

ImmunoHistoChemistry

ELISA IHC

Research Use Only

Polyclonal

0.6 mg/ml

Unconjugated

CCL4

C-C motif chemokine ligand 4

ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4, C-C motif chemokine 4, G-26 T-lymphocyte-secreted protein, MIP-1-beta(1-69), PAT 744, SIS-gamma, T-cell activation protein 2, chemokine (C-C motif) ligand 4, lymphocyte activation gene 1 protein, macrophage inflammatory protein 1-beta, secreted protein G-26, small inducible cytokine A4 (homologous to mouse Mip-1b)

Rabbit

IgG

C-C motif chemokine 4

The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.

-20°C

41116161