CCT128930 (hydrochloride) [2453324-32-6]
HY-13260A
CAS Number2453324-32-6
Product group Chemicals
Estimated Purity98.97
Molecular Weight378.30
Overview
- SupplierMedChem Express
- Product NameCCT128930 (hydrochloride) [2453324-32-6]
- Delivery Days Customer10
- CAS Number2453324-32-6
- CertificationResearch Use Only
- Estimated Purity98.97
- Molecular FormulaC18H21Cl2N5
- Molecular Weight378.30
- Scientific DescriptionCCT128930 hydrochloride is a potent and selective inhibitor of AKT (IC50=6 nM). CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50=168 nM) through the targeting of Met282 of AKT (Met173 of PKA-AKT chimera), as well as 20-fold selectivity over p70S6K (IC50=120 nM). CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. Antitumor activity[1][2].
- SMILESNC1(CC2=CC=C(Cl)C=C2)CCN(C3=C4C(NC=C4)=NC=N3)CC1.[H]Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200
MSDS
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Product group Chemicals
CAS Number2453324-32-6
Estimated Purity98.55%
Molecular Weight378.3
- SizePrice
Product group Chemicals
CCT128930 hydrochlorideM14835
CAS Number2453324-32-6
Molecular Weight378.3
- SizePrice
Product group Chemicals
CCT128930 hydrochlorideORB1300887
CAS Number2453324-32-6
Estimated Purity98.55%
Molecular Weight378.3
- SizePrice