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CCT128930 hydrochloride [2453324-32-6]

CCT128930 hydrochloride [2453324-32-6]

T6303L
TargetMol Chemicals
CAS Number2453324-32-6
Product group Chemicals
Estimated Purity98.55%
Molecular Weight378.3
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    CCT128930 hydrochloride [2453324-32-6]
  • Delivery Days Customer
    9
  • CAS Number
    2453324-32-6
  • Certification
    Research Use Only
  • Chemical Name
    CCT128930 hydrochloride
  • Estimated Purity
    98.55%
  • Molecular Formula
    C18H21Cl2N5
  • Molecular Weight
    378.3
  • Scientific Description
    CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50: 168 nM) through the targeting of Met282 of AKT, as well as 20-fold selectivity over p70S6K (IC50: 120 nM).
  • Shelf life instruction
    3 years
  • SMILES
    Cl.NC1(Cc2ccc(Cl)cc2)CCN(CC1)c1ncnc2[nH]ccc12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200