CD105 antibody [1G2]

GeneTex

CD105 antibody [1G2]

9

1G2 stains endothelial cells from various tissues and syncytiotrophoblasts. Stains intensely on high endothelial venules (HEV), but does not react with peripheral blood cells, this antibody recognizes specifically proerythroblasts from bone marrow.

FACS: Use 2microg for 10^5 cells. Optimal dilutions/concentrations should be determined by the end user.

Flow Cytometry

Research Use Only

Monoclonal

1G2

0.2 mg/ml

Unconjugated

ENG

endoglin

CD105 antigen; END; endoglin; HHT1; ORW1

Mouse

IgG3

Endoglin

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

Human

-20°C or -80°C,2°C to 8°C

12352203