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CD130 antibody [9X23]

GTX52771
GeneTex
ApplicationsWestern Blot
Product group Antibodies
TargetIL6ST
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD130 antibody [9X23]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    9X23
  • Concentration
    500 ug/ml
  • Conjugate
    Unconjugated
  • Gene ID3572
  • Target name
    IL6ST
  • Target description
    interleukin 6 cytokine family signal transducer
  • Target synonyms
    CD130; CD130 antigen; CDW130; GP130; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; gp130, oncostatin M receptor; HIES4; IL-6 receptor subunit beta; IL-6R subunit beta; IL-6RB; interleukin receptor beta chain; interleukin-6 receptor subunit beta; interleukin-6 signal transducer; membrane glycoprotein 130; membrane glycoprotein gp130; oncostatin-M receptor subunit alpha; sGP130
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP40189
  • Protein Name
    Interleukin-6 receptor subunit beta
  • Scientific Description
    The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

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