CD133 antibody [C1C2], Internal
GTX100567
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPROM1
Overview
- SupplierGeneTex
- Product NameCD133 antibody [C1C2], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID8842
- Target namePROM1
- Target descriptionprominin 1
- Target synonymsAC133, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4, prominin-1, AC133 antigen, Retinitis pigmentosa 41, Cone-rod dystrophy 12, antigen AC133, hProminin, hematopoietic stem cell antigen, prominin-like protein 1
- HostRabbit
- IsotypeIgG
- Protein IDO43490
- Protein NameProminin-1
- Scientific DescriptionThis gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Tsai YF, Chan LP, Chen YK, et al. RAD51 is a poor prognostic marker and a potential therapeutic target for oral squamous cell carcinoma. Cancer Cell Int. 2023,23(1):231. doi: 10.1186/s12935-023-03071-wRead this paper
- Cardile A, Passarini C, Zanrè V, et al. Hyperforin Enhances Heme Oxygenase-1 Expression Triggering Lipid Peroxidation in BRAF-Mutated Melanoma Cells and Hampers the Expression of Pro-Metastatic Markers. Antioxidants (Basel). 2023,12(7). doi: 10.3390/antiox12071369Read this paper
- Kim SH, Fan PW, Hsieh CH, et al. The aqueous extract of brucea javanica reduces tumorigenicity of human lung cancer tumorspheres. Cancer Drug Resist. 2021,4(4):866-880. doi: 10.20517/cdr.2021.58Read this paper
- Wu S, Tseng IC, Huang WC, et al. Establishment of an Immunocompetent Metastasis Rat Model with Hepatocyte Cancer Stem Cells. Cancers (Basel). 2020,12(12). doi: 10.3390/cancers12123721Read this paper
- Jao TM, Fang WH, Ciou SC, et al. PCDH10 exerts tumor-suppressor functions through modulation of EGFR/AKT axis in colorectal cancer. Cancer Lett. 2021,499:290-300. doi: 10.1016/j.canlet.2020.11.017Read this paper
- Raineri A, Fasoli S, Campagnari R, et al. Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability. Int J Mol Sci. 2019,20(23). doi: 10.3390/ijms20235980Read this paper
- Wu HY, Yang MC, Ding LY, et al. p21-Activated kinase 3 promotes cancer stem cell phenotypes through activating the Akt-GSK3β-β-catenin signaling pathway in pancreatic cancer cells. Cancer Lett. 2019,456:13-22. doi: 10.1016/j.canlet.2019.04.026Read this paper
- Ma L, Wang L, Shan Y, et al. Suppression of cancer stemness by upregulating Ligand-of-Numb protein X1 in colorectal carcinoma. PLoS One. 2017,12(11):e0188665. doi: 10.1371/journal.pone.0188665Read this paper
- Huang WT, Larsson M, Lee YC, et al. Dual drug-loaded biofunctionalized amphiphilic chitosan nanoparticles: Enhanced synergy between cisplatin and demethoxycurcumin against multidrug-resistant stem-like lung cancer cells. Eur J Pharm Biopharm. 2016,109:165-173. doi: 10.1016/j.ejpb.2016.10.014Read this paper
- Qiu HO, Wang H, Che N, et al. Identification and Characterization of CD133(pos) Subpopulation Cells From a Human Laryngeal Cancer Cell Line. Med Sci Monit. 2016,22:1146-51.Read this paper
Datasheet
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