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ProductsBack/CD133 antibody [C1C2], Internal

CD133 antibody [C1C2], Internal

Research Use Only
GTX100567
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetPROM1
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD133 antibody [C1C2], Internal
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8842
  • Target name
    PROM1
  • Target description
    prominin 1
  • Target synonyms
    AC133; antigen AC133; CD133; CORD12; hematopoietic stem cell antigen; hProminin; MCDR2; MSTP061; prominin-1; prominin-like protein 1; PROML1; RP41; STGD4
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • The aqueous extract of brucea javanica reduces tumorigenicity of human lung cancer tumorspheres. Kim SH et al., 2021, Cancer Drug Resist
    Read more
  • Establishment of an Immunocompetent Metastasis Rat Model with Hepatocyte Cancer Stem Cells. Wu S et al., 2020 Dec 11, Cancers (Basel)
    Read more
  • PCDH10 exerts tumor-suppressor functions through modulation of EGFR/AKT axis in colorectal cancer. Jao TM et al., 2021 Feb 28, Cancer Lett
    Read more
  • Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability. Raineri A et al., 2019 Nov 27, Int J Mol Sci
    Read more
  • p21-Activated kinase 3 promotes cancer stem cell phenotypes through activating the Akt-GSK3beta-beta-catenin signaling pathway in pancreatic cancer cells. Wu HY et al., 2019 Aug 1, Cancer Lett
    Read more
  • Suppression of cancer stemness by upregulating Ligand-of-Numb protein X1 in colorectal carcinoma. Ma L et al., 2017, PLoS One
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  • Dual drug-loaded biofunctionalized amphiphilic chitosan nanoparticles: Enhanced synergy between cisplatin and demethoxycurcumin against multidrug-resistant stem-like lung cancer cells. Huang WT et al., 2016 Dec, Eur J Pharm Biopharm
    Read more
  • Identification and Characterization of CD133(pos) Subpopulation Cells From a Human Laryngeal Cancer Cell Line. Qiu HO et al., 2016 Apr 6, Med Sci Monit
    Read more