CD14 antibody
GTX14006
Overview
- SupplierGeneTex
- Product NameCD14 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID929
- Target nameCD14
- Target descriptionCD14 molecule
- Target synonymsmonocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein
- HostChicken
- IsotypeIgY
- Protein IDP08571
- Protein NameMonocyte differentiation antigen CD14
- Scientific DescriptionCD14 is a single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS)-dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram-negative shock.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203