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CD146 antibody [N1N3]

Name: CD146 antibody [N1N3]
SKU: GTX102413_G10
Availability: BackOrder

GTX102413

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetMCAM

Overview

Supplier
GeneTex
Product Name
CD146 antibody [N1N3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID4162
Target name
MCAM
Target description
melanoma cell adhesion molecule
Target synonyms
CD146; cell surface glycoprotein MUC18; cell surface glycoprotein P1H12; Gicerin; HEMCAM; melanoma adhesion molecule; melanoma-associated antigen A32; melanoma-associated antigen MUC18; MelCAM; METCAM; MUC18; S-endo 1 endothelial-associated antigen
Host
Rabbit
Isotype
IgG
Protein IDP43121
Protein Name
Cell surface glycoprotein MUC18
Scientific Description
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203