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ProductsBack/CD163 antibody [EDHu-1]
IHC-Fr staining of a human tonsil with Mouse anti Human CD163 antibody, clone EDHu-1 (GTX42364), red in A and Mouse anti Human CD21 antibody, clone LB21 (GTX74728), green in B. C is the merged image with nuclei counterstained blue using DAPI. High power
IHC-Fr staining of a human tonsil with Mouse anti Human CD163 antibody, clone EDHu-1 (GTX42364), red in A and Mouse anti Human CD21 antibody, clone LB21 (GTX74728), green in B. C is the merged image with nuclei counterstained blue using DAPI. High power
IHC-Fr staining of a human tonsil with Mouse anti Human CD163 antibody, clone EDHu-1 (GTX42364), red in A and Mouse anti Human CD21 antibody, clone LB21 (GTX74728), green in B. C is the merged image with nuclei counterstained blue using DAPI. High power

CD163 antibody [EDHu-1]

GTX42364
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
TargetCD163
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD163 antibody [EDHu-1]
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    EDHu-1
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9332
  • Target name
    CD163
  • Target description
    CD163 molecule
  • Target synonyms
    M130, MM130, SCARI1, scavenger receptor cysteine-rich type 1 protein M130, hemoglobin scavenger receptor, macrophage-associated antigen
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ86VB7
  • Protein Name
    Scavenger receptor cysteine-rich type 1 protein M130
  • Scientific Description
    The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Ye YS, Pan AZ, Zhen Y, et al. Antipruritic effects of electroacupuncture on morphine-induced pruritus model mice through the TLR2/4-MyD88-NF-κB pathway. Neuroreport. 2019,30(5):331-337. doi: 10.1097/WNR.0000000000001203
    Read this paper
  • Xu Z, Wang L, Tian J, et al. High expression of B7-H3 and CD163 in cancer tissues indicates malignant clinicopathological status and poor prognosis of patients with urothelial cell carcinoma of the bladder. Oncol Lett. 2018,15(5):6519-6526. doi: 10.3892/ol.2018.8173
    Read this paper
  • Yeh YM, Hsu SJ, Lin PC, et al. The c.1085A>G Genetic Variant of CSF1R Gene Regulates Tumor Immunity by Altering the Proliferation, Polarization, and Function of Macrophages. Clin Cancer Res. 2017,23(20):6021-6030. doi: 10.1158/1078-0432.CCR-17-1007
    Read this paper

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