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FACS analysis of THP-1 cells using GTX54458 CD163 antibody [RM3/1]. Black : Cell only control Red : Isotype control Blue : Primary antibody Antibody amount : 2 microg / 2.5x10? cells
FACS analysis of THP-1 cells using GTX54458 CD163 antibody [RM3/1]. Black : Cell only control Red : Isotype control Blue : Primary antibody Antibody amount : 2 microg / 2.5x10? cells
FACS analysis of THP-1 cells using GTX54458 CD163 antibody [RM3/1]. Black : Cell only control Red : Isotype control Blue : Primary antibody Antibody amount : 2 microg / 2.5x10? cells

CD163 antibody [RM3/1]

Research Use Only
GTX54458
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman, Monkey, Mouse
TargetCD163
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    CD163 antibody [RM3/1]
  • Delivery Days Customer
    9
  • Antibody Specificity
    The RM3/1 antigen expression is restricted to human monocytes and macrophages that evolve in the late phase of inflammation, predominantly macrophages of healing tissue.,We do not recommend use of this product for Guinea pig,Pig,Rat.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    rm3/1
  • Concentration
    100 ug/ml
  • Conjugate
    Unconjugated
  • Gene ID9332
  • Target name
    CD163
  • Target description
    CD163 molecule
  • Target synonyms
    hemoglobin scavenger receptor; M130; macrophage-associated antigen; MM130; SCARI1; scavenger receptor cysteine-rich type 1 protein M130
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
  • Reactivity
    Human, Monkey, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Immunosuppressive Features of the Microenvironment in Lymph Nodes Granulomas from Tuberculosis and HIV-Co-Infected Patients. Ashenafi S et al., 2022 Apr, Am J Pathol
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  • HOXA5 induces M2 macrophage polarization to attenuate carotid atherosclerosis by activating MED1. Jing Y et al., 2021 Sep, IUBMB Life
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  • Effects of scavenger receptors-1 class A stimulation on macrophage morphology and highly modified advanced glycation end product-protein phagocytosis. Hamasaki S et al., 2018 Apr 12, Sci Rep
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  • Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis. Kobori T et al., 2018, Front Immunol
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