CD18 antibody [MEM-148] (Low Endotoxin)
GTX28220-00
ApplicationsFunctional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman
TargetITGB2
Overview
- SupplierGeneTex
- Product NameCD18 antibody [MEM-148] (Low Endotoxin)
- Delivery Days Customer9
- Antibody SpecificityThis antibody recognizes an epitope on CD18 which is essentially inaccessible in intact integrin molecules on resting leukocytes, but is exposed on high-affinity state of LFA-1 or on unassociated CD18.,We do not recommend use of this product for Pig.
- ApplicationsFunctional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMEM-148
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3689
- Target nameITGB2
- Target descriptionintegrin subunit beta 2
- Target synonymsCD18; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; integrin beta chain, beta 2; integrin beta-2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); LAD; LCAMB; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; LFA-1; MAC-1; MF17; MFI7; truncated integrin beta-2
- HostMouse
- IsotypeIgG1
- Protein IDP05107
- Protein NameIntegrin beta-2
- Scientific DescriptionThis gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Distinct binding affinities of Mac-1 and LFA-1 in neutrophil activation. Li N et al., 2013 Apr 15, J ImmunolRead more